Treatment was deemed to be always a success in 91% of patients as judged by the investigator and 90% when assessed by the individual themselves 11 . Gastro-oesophageal reflux (GER) and the outward symptoms of heartburn and regurgitation are normal in pregnancy. These symptoms are transient and mostly resolve postpartum but have a negative impact on standard of living. Here, we present a prospective clinical evaluation of the safety and efficacy of an alginate raft-forming oral suspension that is licensed for use in pregnancy. The study was a multicentre, prospective, open-label, and baseline-controlled study of Liquid Gaviscon (LG) in the treating heartburn in pregnant women with current outward indications of heartburn and/or reflux requiring treatment (recruited 144).
Adverse fetal outcomes were not reported [Larson et al, 1997]. This study had not been contained in the Cochrane systematic review due to its crossover design [Phupong and Hanprasertpong, 2015].
MAY I take Gaviscon double action while pregnant or breastfeeding?
Products whose principal ingredient is really a calcium salt are widely available over-the-counter, but are only recommended by CKS for short-term or occasional use. Calcium products have already been reported to cause rebound acid reflux on discontinuation [BNF 72, 2016], and rarely, excessive calcium intake could cause milk-alkali syndrome (seen as a hypercalcaemia, alkalosis, and renal failure) [American Gastroenterological Association, 2006; Schaefer et al, 2015]. Advance cites data from clinical studies (including a lot more than 500 pregnant women) and post-marketing experience which will not show fetal toxicity or malformations [ABPI Medicines Compendium, 2014]. Antacids have not been found to cause teratogenic effects in animal studies [van der Woude et al, 2014] and calcium, aluminium, and magnesium-containing preparations (except magnesium trisilicate) are usually safe in pregnancy at the most common doses [Ali and Egan, 2007; Body and Christie, 2016]. If symptoms are severe, or persist despite treatment having an antacid or alginate, consider prescribing an acid-suppressing drug.
Causes of heartburn in pregnancy
You can aquire antacids from pharmacies and supermarkets. Like Gaviscon, these medicines are reflux suppressants.
â€œFood items and substances can make indigestion worse, if you have not stopped already due to your pregnancy then stopping smoking can help, as can stopping alcohol. Calcium carbonate and sodium bicarbonate are both antacids and work by neutralising excess acid and protect the stomach from irritation. Itâ€™s important to note – what many papers didn’t
Dyspepsia in pregnancy is predominantly due to gastro-oesophageal reflux disease (GORD). The diagnosis can be made on symptoms alone, which usually do not change from the non-pregnant population. Once gastro-oesophageal reflux symptoms have developed, you will find a high likelihood (approximately 50% each trimester) of the outward symptoms persisting during the pregnancy. However, generally in most women, symptoms can be improved with lifestyle modifications and will disappear shortly after delivery.
9. Uzan M, Uzan S, Sureau C, Richard-Berthe C. Pyrosis and regurgitations during pregnancy. Efficacy and innocuousness of a treatment with Gaviscon suspension. 5. Bor S, Kitapcioglu G, Dettmar P, Baxter T. Association of heartburn during pregnancy with the chance of gastroesophageal reflux disease.
If you experience side effects, ask your GP or pharmacist about trying another medicine. The types of medicine which may be prescribed for indigestion during pregnancy are described below. The gastric acid breaks down the mucosa, which in turn causes irritation and leads to the symptoms of indigestion. The symptoms of indigestion (dyspepsia) are caused by stomach acid coming into contact with the sensitive, protective lining (mucosa) of one’s digestive system. You may experience indigestion at any point throughout your pregnancy, although your symptoms may be more frequent and severe during your third trimester (from week 27 before birth of the infant).
Bor et al.  showed that in Turkey heartburn in pregnancy increased the chance of experiencing heartburn 1 year later and that the chance increased with the number of births (baseline 6.4%, 1 delivery 17.7%, 2 deliveries 36.1%). The result of heartburn and acid reflux disorder on the severe nature of nausea and vomiting of pregnancy. A Cochrane systematic review on interventions for heartburn in pregnancy (search date June 2015) found a small study of 30 women in that your intervention group received ranitidine 75 mg daily plus antacids and the control group were given placebo plus antacids. The Cochrane authors reported no data with regards to their agreed outcomes but noted that nearly half of the ladies in the placebo and antacid group discontinued the study drug due to inadequate symptom relief, compared with no discontinuations in the ranitidine and antacid group [Phupong and Hanprasertpong, 2015]. The symptoms of heartburn and indigestion will be the same for anybody else who suffers.
Many women suffer from both heartburn (acid reflux disorder) and indigestion during pregnancy also it tends to are more common because the pregnancy progresses. In fact, it can arise as soon as the next trimester. Many women are frightened to take medication for heartburn throughout their pregnancy, because they are afraid it’ll harm their baby.
The end result is that, if heartburn during pregnancy is something you canâ€™t manage or prevent with your diet, itâ€™s better to try a mix of treatments, versus taking an excessive amount of one thing. So, why arenâ€™t there warnings about side effects?
This may irritate your stomach lining and make your symptoms worse. Proton pump inhibitors (PPIs) reduce the quantity of acid your stomach produces. Most PPIs can be found on prescription only – they include omeprazole and lansoprazole.